TNF Pathophysiology PDF
By:George Kollias,Petros P. Sfikakis
Published on 2010-01-01 by Karger Medical and Scientific Publishers
TNF is a multifunctional proinflammatory cytokine central to the development and homeostasis of the immune system and a regulator of cell activation, differentiation and death. Recent decades have seen an enormous scientific and clinical interest in the function of TNF in physiology and disease. A vast amount of data has been accumulated at the biochemical, molecular and cellular level, establishing TNF as a prototype for in-depth understanding of the physiological and pathogenic functions of cytokines. This volume covers several current aspects of TNF regulation and function, including transcriptional and posttranscriptional control mechanisms, cellular modes of action, signaling networks that mediate its effect, involvement in pathogenesis and clinical outcomes of TNF antagonists. It combines basic science at the molecular and cellular level with research in animal models of disease and clinical findings to provide a comprehensive review of recent developments in TNF biology. A thorough understanding of the mechanisms by which this key molecular player is produced and functions to regulate cell biology, immunity and disease postulates novel paradigms on how genes contribute to the development and physiology of biological systems.
This Book was ranked at 17 by Google Books for keyword Pathophysiology.
Book ID of TNF Pathophysiology's Books is ffvUswWZCJsC, Book which was written byGeorge Kollias,Petros P. Sfikakishave ETAG "5HYRx9r6gm0"
Book which was published by Karger Medical and Scientific Publishers since 2010-01-01 have ISBNs, ISBN 13 Code is 9783805593830 and ISBN 10 Code is 380559383X
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Book which have "215 Pages" is Printed at BOOK under CategoryMedical
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